The ethical value—and to some scholars, necessity—of providing trial patients with post-trial access (PTA) to an investigational drug has been subject to significant attention in the field of research ethics. Although no consensus has emerged, it seems clear that, in some trial contexts, various factors make PTA particularly appropriate. We outline the atypical aspects of psychedelic clinical trials that support the case for introducing the provision of PTA within research in this field, including the broader legal status of psychedelics, the (...) nature of the researcher-therapist/participant relationship, and the extended time-frame of the full therapeutic process. As is increasingly understood, the efficacy of psychedelic-assisted psychotherapy is driven as much by extrapharmacological elements and the cultural therapeutic container as by the drug itself. As such, we also advocate for a refocusing of attention from post-trial access to a broader concept encompassing other elements of post-trial care. We provide an overview of some of the potential post-trial care provisions that may be appropriate in psychedelic clinical trials. Although the World Medical Association’s Declaration of Helsinki calls on researchers, sponsors, and governments to make provisions for post-trial access, such provision may feel impracticable or out-of-reach within psychedelic trials that are already constrained by a high resource demand and significant bureaucratic burden. We show how conceiving of post-trial provision as an integral site of the research process, and an appropriate destination for research funding, will serve to develop the infrastructure necessary for the post-legalisation psychedelic medicine ecosystem. (shrink)

Most of all, this book introduces readers to a genuine lover of wisdom, a philosopher who used ordinary English to address traditional problems of philosophy.

Caring for the stranger -- Why compassion in politics? -- Historical perspectives on social welfare and global development -- Historical perspectives on human rights -- Compassion in religious and secular thought -- Justice and moral responsibility -- Altruism, empathy, and the making of "Us" and "Them" -- The moral politics of Liberals and Conservatives -- Politics against compassion in the United States -- Compassion in public policy and law -- Creating a more compassionate and just society.

Did the September 11, 2001 terrorist attacks on the U.S. cause the values of teenagers in the U.S. to change? Did their previously important self-esteem and self-actualization values become less important and their survival and safety values become more important? Changes in the values of teenagers are important for practitioners, managers, marketers, and researchers to understand because high school students are our current and future employees, managers, and customers, and research has shown that values impact work and consumer-related attitudes and (...) behaviors. Further, studies that compared higher to lower performing for-profit and not-for-profit companies have found that higher performing organizations had strong values that permeated their organizations [Collins J. C., and J. I. Porras: 1994, Built to Last: Successful Habits of Visionary Companies (New York, Harper Business); O’Reilly, C. A. and J. A. Chatman: 1996, in B. M. Staw and L. L. Cummings (eds.), Research in Organizational Behavior, vol. 18 (JAI Press, Greenwhich, CT), pp. 157–200; O’Reilly, C. A.: 1989, California Management Review 31(4), 9–25; Posner, B. Z., and W. H. Schmidt: 1996, Public Personnel Management, 25(3), 277–298; Rousseau, D.: 1990, Group and Organization Studies 15(4), 448–460; Schein, E. H.: 2004, Organizational Culture and Leadership. San Francisco, Jossey Bass)]. While one study of adults found value changes, no known studies have explored if the values of teenagers also changed post-9/11. This study filled that research gap by exploring the values of a random sample of 1000 U.S. teenagers in grades 9 to 12 pre- and post-9/11, using a demographic questionnaire and the Rokeach Value Survey. The research results indicated that teenage survival, safety, and security values (a world at peace, freedom, national security, and salvation) increased in importance while their self-esteem and self-actualization values (a sense of accomplishment, inner harmony, pleasure, self-respect, and wisdom) decreased in importance, mirroring the changes for adults. The meaning of these findings for practitioners, managers, marketers and researchers was discussed. (shrink)

BackgroundThere is a growing interest in using cognitive–behavioural therapy (CBT) with people who have Asperger syndrome and comorbid mental health problems.AimsTo examine whether modified group CBT for clinically significant anxiety in an Asperger syndrome population is feasible and likely to be efficacious.MethodUsing a randomised assessor-blind trial, 52 individuals with Asperger syndrome were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to treatment were followed (...) up for 24 weeks.ResultsThe conversion rate for this trial was high (1.6:1), while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared with those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety.ConclusionsTrials of psychological therapies with this population are feasible. Larger definitive trials are now needed. (shrink)

This study was a preliminary exploration of the value changes taking place in the United States since the September 11, 2001 terrorist attack on the World Trade Center in New York, which was a significant emotional event or cultural upheaval. Rokeach told us that "a person's total value system may undergo change as a result of socialization, therapy, or cultural upheaval..." (Rokeach, The Nature of Human Values, 1973, p. 37). The researchers explored the value changes of 500 aviation industry employees (...) before the attack and 500 after the attack. The statistically significant research results showed a total of twenty-seven of thirty-six values changed. Before the attack respondents valued much higher self-esteem and self-actualization values like A Sense of Accomplishment and Self-Respect. After the attack respondents placed a much higher value importance on survival, safety and security values like A World at Peace, Freedom, Family Security, National Security, Mature Love, Salvation, and True Friendship. (shrink)

The extent to which British Idealism was heavily influenced by Scots has been little noticed, yet not only were they at the forefront of introducing Hegel into Britain in the work of Ferrier, Carlyle, Hutcheson, Stirling and Edward Caird, but they were also distinctive in locating themselves in relation to the Scottish philosophical tradition they sought to extend. The Scottish Idealists, among them Edward Caird, David George Ritchie, Andrew Seth Pringle Pattison, William Mitchell, John Watson, and the Welshman (...) Henry Jones who found his spiritual home in Glasgow, comprised a formidable force and dominated the philosophical professoriate in Britain, Australia and Canada from the late nineteenth century to the years leading up to the First World War. Its main centres were St. Andrews, Glasgow and Edinburgh in Scotland, Cardiff in Wales, and Oxford in England. This collection of readings, the first of its kind, has been chosen with a view to displaying the variety, richness and strength of the Scottish Idealist tradition, beginning with an essay from the famous Essays in Philosophical Criticism, a book that set-out the future direction of enquiry for this group of thinkers who shared a 'common purpose or tendency'. Scottish Idealism was immensely spiritual in character and recognized no hard and fast distinctions between philosophy, religion, poetry and science. It was a formidable force in social and educational reform.. (shrink)

Thus far in the development of the discipline of medical ethics, the overriding concern has been with solutions to specific problems. But discussion is hampered by lack of understanding of the scope and methodology of medical ethics, and its scientific and philosophical basis. In Underpinnings of Medical Ethics Edmond A. Murphy, James J. Butzow, and Edward L. Suarez-Murias offer much-needed clarification of the purview, ontological basis, and methodology of a medical ethics that is to be comprehensive and yet (...) readily accepted by all. The authors begin by describing the scope of the analysis and discussing possible ethical systems and paradigms. They then deal with the structures and concepts necessary in the formulation of a coherent philosophy: normality and disease, scientific and juridical law, certainty and certitude, decisions. Finally, they introduce particular human dimensions, such as quality of life, pain, and responsibility. Throughout, case examples illustrate the authors' theoretical framework. (shrink)

Scientists, both modern and contemporary, commonly try to discern patterns in nature. They also frequently use arguments by analogy to construct an understanding of the natural mechanisms responsible for producing such patterns. For Robert Boyle, the famous clock at Strasbourg provided a perfect paradigm for understanding the connection between these two scientific activities. Unfortunately, it also posed a serious threat to his realistic pretensions. All sorts of internal mechanisms could produce precisely the same movements across the face of a clock. (...) Given God's immense creative capacities, Boyle realized that standard epistemological constraints could never ensure, not even to the least degree of probability, that scientific theories about the unobservable mechanisms of nature were descriptively accurate. Like most moderns, he fortified his epistemology theologically in order to retain his realistic stance. John Locke, however, took counsel from Ecclesiastes to repudiate Boyle's realism, while Samuel Clarke mobilized biblical images to dismiss the clockwork paradigm altogether.A contemporary review of this modern controversy reveals that there is still much to learn from the clock at Strasbourg. Among other things, the realism/antirealism issue is of central importance to understanding today's science, Nancey Murphy's protests notwithstanding. Moreover, the kind of realistic stance that is essential, not only to the truth but to the very intelligibility of certain types of scientific explanation, demands more than the critical realism of Ian Barbour. To be taken seriously, the models used in such contexts must be taken literally. (shrink)

While ante rem structuralism offers a promising account of mathematical truth and mathematical ontology, several of the most prominent formulations of the view seem to be subject to significant difficulties involving the identity conditions of the objects they posit. In this paper I argue that those difficulties can be overcome by adopting encoding structuralism, a version of realism about mathematical objects developed by Bernard Linsky, Uri Nodelman and Edward Zalta.

Andrew Benjamin’s book Disclosing Spaces (2004) presents a theory of painting. The theory is developed via a meticulous analysis of a series of individual artworks. The pivot of Benjamin’s theory of painting is the idea of relationality. The theory is critically reviewed with reference to the works of Edward Hopper, Gerhard Richter and Jacques-Louis David.

Edward Aloysius Pace, philosopher and educator, by J. H. Ryan.-Neo-scholastic philosophy in American Catholic culture, by C. A. Hart.- The significance of Suarez for a revival of scholasticism, by J. F. McCormick.- The new physics and scholasticism, by F. A. Walsh.- The new humanism and standards, by L. R. Ward.- The purpose of the state, by E. F. Murphy.- The concept of beauty in St. Thomas Aquinas, by G. B. Phelan.- The knowableness of God: its relation to the (...) theory of knowledge in St. Thomas, by Matthew Schumacher.- The modern idea of God, by F. J. Sheen.- The analysis of association of its equational constants, by T. V. Moore.- Bibliography (p. 224-225) - Character and body build in children, by Sister M. Rosa McDonough. Bibliography (p. 248-249) - The moral development of children, by Sister Mary.- Medieval education (700-900) by T. J. Shahan.- The need for a Catholic philosophy of education, by George Johnson. (shrink)

Institutional pedagogy is a radical educational practice that began in France in the first half of the twentieth century. It aims to transform the material context of learning in order to empower students to collectively take responsibility for their own lives. As an analysis of the effects of this practice on the work of Félix Guattari, the purpose of this article is twofold. First, it aims to describe the theoretical and practical cross-pollination that occurred between the two movements of institutional (...) pedagogy and institutional psychotherapy. Second, it argues for a new methodology for reading the published works of Félix Guattari in the context of institutional pedagogy. The article begins with a brief analysis of the work of Celéstin Freinet, followed by an account of the development of his techniques by Aïda Vasquez, Fernand Oury, Jean Oury and Guattari. After showing how these practices informed Guattari’s work as a political activist, in the final section I argue that we should treat the figure of Félix Guattari as a special kind of ‘writing machine’. (shrink)

We often impute responsibility to others for the purpose of retributive punishment - sometimes hoping that they receive the level of suffering proportional to what Kant calls their "inner wickedness". But do we know enough to do this without reckless error? Are we morally pure enough to do this without hypocrisy? The present essay explores these two questions. Oftmals rechnen wir anderen Verantwortlichkeit zu, um durch Strafe Vergeltung zu üben - und dies manchmal in der Hoffnung, daß ihnen gerade der (...) Grad an Leid zugefügt wird, der im rechten Verhältnis zu dem steht, was Kant "innere Bösartigkeit" nennt. Aber wissen wir eigentlich genug, um dies ohne grobe Fahrlässigkeit, und sind wir moralisch rein genug, um dies ohne Heuchelei tun zu können? Der vorliegende Beitrag befaßt sich mit diesen beiden Fragen. (shrink)

With _Trilogy of Resistance_, the political philosopher Antonio Negri extends his intervention in contemporary politics and culture into a new medium: drama. The three plays collected for the first time in this volume dramatize the central concepts of the innovative and influential thought he has articulated in his best-selling books _Empire_ and _Multitude_, coauthored with Michael Hardt. In the tradition of Bertolt Brecht and Heiner Müller, Negri’s political dramas are designed to provoke debate around the fundamental questions they raise about (...) resistance, violence, and tyranny. In _Swarm_, the protagonist searches for an effective mode of activism; with the help of a Greek-style chorus, she tries on different roles, from the suicide bomber and party apparatchik to the multitude. _The Bent Man_, set in fascist Italy, focuses on a woodcutter who resists fascism by bending himself in two and using his own now-twisted body as a weapon against war. In _Cithaeron_, perhaps the most audacious of the three plays, Negri reworks Euripides’s _Bacchae_ to explore the circumstances that would compel a diverse and creative community to withdraw from both the despotic government that constrains it and the traditional family relationships that reinforce that despotism. First published in France in 2009 and featuring an introduction by Negri, _Trilogy of Resistance_ provides a direct and passionate distillation of Negri’s concepts and offers insights into one of the most important projects in political philosophy currently under way, as well as a timely reminder of the power of theater to effectively dramatize complex and challenging ideas. (shrink)

Machine generated contents note: Part I. Introduction: 1. Personal epistemology in the classroom: a welcome and guide for the reader Florian C. Feucht and Lisa D. Bendixen; Part II. Frameworks and Conceptual Issues: 2. Manifestations of an epistemological belief system in pre-k to 12 classrooms Marlene Schommer-Aikins, Mary Bird, and Linda Bakken; 3. Epistemic climates in elementary classrooms Florian C. Feucht; 4. The integrative model of personal epistemology development: theoretical underpinnings and implications for education Deanna C. Rule and Lisa D. (...) Bendixen; 5. An epistemic framework for scientific reasoning in informal contexts Fang-Ying Yang and Chin-Chung Tsai; Appendices; 6. Who knows what and who can we believe? Epistemological beliefs are beliefs about knowledge (mostly) to be attained from others Rainer Bromme, Dorothe Kienhues, and Torsten Porsch; Part III. Students' Personal Epistemology, its Development, and Relation to Learning: 7. Stalking young persons' changing beliefs about belief Michael J. Chandler and Travis Proulx; 8. Epistemological development in very young knowers Leah K. Wildenger, Barbara K. Hofer, and Jean E. Burr; 9. Beliefs about knowledge and revision of knowledge: on the importance of epistemic beliefs for intentional conceptual change in elementary and middle school students Lucia Mason; 10. The reflexive relation between students' mathematics-related beliefs and the mathematics classroom culture Erik De Corte, Peter Op 't Eynde, Fien Depaepe, and Lieven Verschaffel; 11. Examining the influence of epistemic beliefs and goal orientations on the academic performance of adolescent students enrolled in high-poverty, high-minority schools P. Karen Murphy, Michelle M. Buehl, Jill A. Zeruth, Maeghan N. Edwards, Joyce F. Long, and Shinichi Monoi; 12. Using cognitive interviewing to explore elementary and secondary school students' epistemic and ontological cognition Jeffrey A. Greene, Judith Torney-Purta, Roger Azevedo, and Jane Robertson; Part IV. Teachers' Personal Epistemology and its Impact on Classroom Teaching: 13. Epistemological resources and framing: a cognitive framework for helping teachers interpret and respond to their students' epistemologies Andrew Elby and David Hammer; 14. The effects of teachers' beliefs on elementary students' beliefs, motivation, and achievement in mathematics Krista R. Muis and Michael J. Foy; Appendices; 15. Teachers' articulation of beliefs about teaching knowledge: conceptualizing a belief framework Helenrose Fives and Michelle M. Buehl; Appendices; 16. Beyond epistemology: assessing teachers' epistemological and ontological world views Lori Olafson and Gregory Schraw; Part V. Conclusion: 17. Personal epistemology in the classroom: what does research and theory tell us and where do we need to go next? Lisa D. Bendixen and Florian C. Feucht. (shrink)